CBD and the Endocannabinoid System

CBD and the Endocannabinoid System

Cannabidiol (CBD) is one of several active compounds in the cannabis sativa plant. In order to understand how CBD works, we first need to explore the Endocannabinoid System and its role in in regulating our immune system, moods, perceptions of pain, memory functions, appetite and temperature regulation.
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INTRODUCTION

Cannabidiol (CBD) is one of several active compounds in the cannabis sativa plant. In recent years, researchers have studied its therapeutic value and interaction with the human body to understand its potential. 

In order to understand how CBD works, we first need to explore the Endocannabinoid System and its role in regulating our immune system, moods, perceptions of pain, memory functions, appetite and temperature regulation.

WHAT IS THE ENDOCANNABINOID SYSTEM (ECS)?

The human body has a built-in regulatory system known as the Endocannabinoid System (ECS) which is made up of a network of specialised receptors, neurotransmitters and enzymes that are primarily responsible for promoting and maintaining homeostasis.

The ECS plays an important role in keeping all of our biological systems in balance, regulating a number of critical physical and mental processes such as mood, sleep cycles, stress response, appetite, memory, muscle control, and more.

Did you know? All animals, including vertebrates and invertebrates, have been found to have an endocannabinoid system! 

We naturally produce endogenous (internal) cannabinoids, called ‘endocannabinoids’, which correspond to the relevant receptors in our bodies. Cannabinoids derived from the hemp plant are known as exogenous cannabinoids as they come from external sources instead. 

Cannabinoid receptors are found all over your body, including your immune system, your central nervous system, and even in your brain. Fundamentally, the two main types of receptors are known as CB1 and CB2 receptors - both of which the majority of cannabinoids can bind to. 

Since CBD is a cannabinoid, it is thought to go hand in hand with the ECS by interacting with these receptors in the body to produce therapeutic effects.

However, while CBD stimulates and interacts with both CB1 and CB2 receptors, it does not directly bind with either of them and instead activates others, such as serotonin and adenosine receptors, giving it the ability to influence the Endocannabinoid System in a unique and powerful way. 

While we all feel an impact on our sleep, our emotions, or our energy levels from time to time, you can support your own ECS with the addition of CBD infused products to sustain optimal health and wellbeing. 

Full-spectrum CBD products are considered most effective and can offer a range of enhanced benefits for helping reduce anxiety, stress, pain and depression through the stimulation of the Entourage Effect which we’ll talk about next. 

Here is a list of examples of some physiological functions that may be improved with CBD: 

  • Sleep & energy
  • Mood & motivation
  • Stress response 
  • Muscle movement & control
  • Memory & concentration

THE ENTOURAGE EFFECT

As we’ve mentioned, CBD is one of the many active compounds that can be extracted from the hemp plant. But, when CBD and other compounds work together rather than in isolation within our bodies, their synergistic effects can be enhanced to provide even greater benefits… This theory is called the Entourage Effect, which is possible only in full-spectrum CBD products, like ours. 

Each cannabinoid in the cannabis plant has its own unique properties that combine to enhance their performance and therapeutic effects to provide positive mental and physical benefits. 

Along with cannabinoids, there are other active compounds, including terpenoids and flavonoids - both of which are found in our Full Spectrum CBD products. These organic compounds influence how CBD can affect the Endocannabinoid System...

Terpenoids are aromatic compounds that bring you the vibrant smells and flavours that are found in some of our CBD products. They are responsible for the fresh citrus scent and taste of a tangerine, or the calming smell of lavender, for instance. 

Terpenes are found in almost every flower, herb, and fruit! 

Similarly, flavonoids also contribute to the aroma and flavour profiles, but interact with the body differently to offer their own unique therapeutic effects. They are generally rich with antioxidants and can help regulate cellular activity and protect the body from toxins. 

Flavonoids found specifically in cannabis plants are known as cannaflavins!

These compounds can be found together in Full Spectrum CBD products and, when combined with CBD, can provide a range of therapeutic benefits by engaging the Endocannabinoid System and helping to create the Entourage Effect. 

Here at Natural Greens, we use the whole hemp plant to produce full spectrum CBD oil that contains all of the naturally occurring cannabinoids that can stimulate the Entourage Effect, which pure CBD isolate products cannot!